What It Is
MTHFR & BHMT Assist (Methyl Boost) is a B-vitamin formula supplying folate in two forms, B12 as hydroxocobalamin, and active forms of B2 and B6, alongside TRAACS® chelated magnesium and zinc and a 1020 mg blend containing betaine, sunflower lecithin, and glandular ingredients.
Key Benefits
- Supplies folate at 4250 mcg DFE, split between folinic acid and L-5-methyltetrahydrofolate
- Provides vitamin B12 as hydroxocobalamin, a non-methylated form
- Supplies B2 as riboflavin-5-phosphate and B6 as pyridoxal-5-phosphate, both active phosphorylated forms
- Provides magnesium and zinc as Albion® TRAACS® bisglycinate chelates
- Supplies betaine anhydrous, also known as trimethylglycine, a methyl donor used in normal methylation pathways
- Includes sunflower lecithin providing phosphatidylserine and phosphatidylcholine
How It Works
Folate is supplied in two forms rather than one: 25% as folinic acid and 75% as L-5-methyltetrahydrofolate. Both are reduced folates, distinct from folic acid, and the label states the split explicitly.
Vitamin B12 is supplied as hydroxocobalamin. B12 appears in supplements in several forms — cyanocobalamin, methylcobalamin, adenosylcobalamin, and hydroxocobalamin among them — and this formula specifies the hydroxo form, which is not methylated.
B2 and B6 are provided as riboflavin-5-phosphate and pyridoxal-5-phosphate, the phosphorylated forms the body uses directly as cofactors.
Magnesium and zinc are supplied as Albion® TRAACS® bisglycinate chelates, minerals bound to the amino acid glycine rather than delivered as simple salts.
Featured Ingredients
- Folate, 4250 mcg DFE (2500 mcg) — 25% folinic acid, 75% L-5-methyltetrahydrofolate
- Vitamin B12 as hydroxocobalamin, 1000 mcg
- Niacin, 75 mg
- Vitamin B1 as thiamin HCl and vitamin B2 as riboflavin-5-phosphate, 20 mg each
- Vitamin B6 as pyridoxal-5-phosphate, 10 mg
- Biotin, 400 mcg
- Magnesium and zinc as TRAACS® bisglycinate chelates, 15 mg each
- Betaine anhydrous (TMG) and sunflower lecithin supplying phosphatidylserine and phosphatidylcholine
- Glandular ingredients — stomach tissue, duodenal substance, pancreatin, and intrinsic factor
- Lithium as lithium orotate
Supplement Facts
Serving Size: 2 Capsules
Servings Per Container: 45
| Amount Per Serving | % Daily Value |
|---|---|
| Vitamin B-1 (Thiamin HCl) | 20 mg, 1667% |
| Vitamin B-2 (Riboflavin-5-Phosphate) | 20 mg, 1538% |
| Niacin | 75 mg, 469% |
| Vitamin B-6 (Pyridoxal-5-Phosphate) | 10 mg, 588% |
| Folate | 4250 mcg DFE (2500 mcg), 1063% |
| (as 25% folinic acid; 75% L-5-Methyltetrahydrofolate) | |
| Vitamin B-12 (Hydroxocobalamin) | 1000 mcg, 41667% |
| Biotin (pure) | 400 mcg, 1333% |
| Magnesium (as Bisglycinate Chelate) TRAACS® | 15 mg, 4% |
| Zinc (Zinc Bisglycinate Chelate)(TRAACS®) | 15 mg, 136% |
| Proprietary Blend | 1020 mg, * |
| Betaine Anhydrous (TMG) | |
| Stomach Tissue | |
| Lecithin (from Sunflower) | |
| Phosphatidylserine | |
| Phosphatidylcholine | |
| Duodenal Substance | |
| Pancreatin | |
| Intrinsic Factor | |
| Lithium (Lithium Orotate) | |
* Daily Value not established.
Other Ingredients: Hypromellose and water (vegetarian capsule)
Sourcing & Quality
Magnesium and zinc are supplied as patented Albion® TRAACS® amino acid chelates. Folate is provided as two reduced forms with the ratio stated on the label, and B2 and B6 are supplied in their active phosphorylated forms. The lecithin is sunflower-derived rather than soy. The capsule shell is hypromellose, a plant-derived vegetarian capsule, and the formula is gluten-free.
This formula is not vegetarian. It contains stomach tissue, duodenal substance, pancreatin, and intrinsic factor, all animal-derived. The vegetarian capsule shell describes the shell only, not the contents.
Warnings
- Contains animal-derived glandular ingredients. Not suitable for vegetarians or vegans.
- This formula supplies several nutrients well above 100% of the Daily Value, including vitamin B12 at 41,667%. Do not exceed the suggested use, and consult your healthcare professional before combining it with other B-vitamin products.
- Keep out of reach of children.
- Consult your healthcare professional before use if pregnant, nursing, taking medications, or under medical supervision.
- Store in a cool, dry place.
Frequently Asked Questions
Is this formula vegetarian?
No. The capsule shell is hypromellose, which is plant-derived, but the formula contains stomach tissue, duodenal substance, pancreatin, and intrinsic factor, all of which are animal-derived. A vegetarian capsule shell describes the shell only, not what is inside it. The formula is gluten-free.
What is in MTHFR & BHMT Assist?
Each 2-capsule serving supplies 20 mg each of vitamins B1 and B2, 75 mg of niacin, 10 mg of B6, 4250 mcg DFE of folate, 1000 mcg of B12 as hydroxocobalamin, 400 mcg of biotin, and 15 mg each of magnesium and zinc as TRAACS chelates. It also includes a 1020 mg proprietary blend containing betaine anhydrous, stomach tissue, sunflower lecithin providing phosphatidylserine and phosphatidylcholine, duodenal substance, pancreatin, intrinsic factor, and lithium orotate. The full panel is listed in the Supplement Facts above.
What form does it come in, and how many servings are in a bottle?
The formula is supplied in capsules with a hypromellose shell. A bottle contains 90 capsules and the serving size is 2 capsules, which works out to 45 servings per bottle.
What form of B12 does this contain?
Hydroxocobalamin, at 1000 mcg per serving. Vitamin B12 appears in supplements as several different forms — cyanocobalamin, methylcobalamin, adenosylcobalamin, and hydroxocobalamin. Hydroxocobalamin is not a methylated form. The label specifies which form is used.
Why is the folate listed in two forms?
The label states the folate is 25% folinic acid and 75% L-5-methyltetrahydrofolate. Both are reduced folates, which are distinct from folic acid. Supplying two forms rather than one is a formulation choice, and stating the ratio on the panel is more detail than most labels give.
What does TRAACS mean on the magnesium and zinc?
TRAACS is a branded chelate technology from Albion. A chelated mineral is bound to an amino acid — glycine, in the case of a bisglycinate — rather than supplied as a simple mineral salt such as an oxide or a citrate. The label names the specific chelate for each mineral.
Why are so many nutrients above 100% of the Daily Value?
Daily Values are reference amounts set for general population labelling, and B vitamins are water-soluble, so supplement formulas frequently supply multiples of them. In this formula seven nutrients exceed 100%, with B12 the highest at 41,667% of its 2.4 mcg Daily Value. The warnings section above notes this and advises against combining it with other B-vitamin products without guidance.
