ABP1 Assist (HISTA/GUT) contains diamine oxidase (DAO), an enzyme naturally found in the digestive tract that degrades histamine and other biogenic amines. This professional-grade supplement also supplies vitamin B6 (as pyridoxal-5′-phosphate) — a required cofactor for DAO function — along with apple polyphenols, rutin, and lyophilized thymus and kidney tissue to provide comprehensive support for histamine balance and immune modulation.
Two capsules provide sufficient DAO activity to degrade approximately 75,000 μM/hour of histidine (histamine precursor). DAO enzyme activity is sourced exclusively from New Zealand bovine kidney tissue, known for its purity and safety.
Key Mechanisms and Highlights
- DAO Enzyme: Facilitates histamine degradation and supports gut comfort.
- Vitamin B6 (P-5-P): Essential cofactor that enhances DAO enzyme activity.
- Apple Polyphenols & Rutin: Provide antioxidant and histamine-modulating support; may benefit those with sensitivities or seasonal discomforts.
- Thymus Glandular (Ovine): Source of endogenous DAO and immune-supportive cofactors.
This formulation pairs well with Histamine Scavenger and MC Balancer for layered histamine-scavenging support.
Key Benefits
- Supports the body’s natural ability to metabolize histamine‡
• Promotes a healthy inflammatory and immune response‡
• Provides cofactors and antioxidants that assist DAO enzyme function‡
• Encourages gastrointestinal and mucosal balance‡
• Ideal for those with histamine or food-related sensitivities‡
Product Highlights
- Professional-grade DAO and nutrient blend
- Delayed-release capsules for optimal intestinal delivery
- Gluten Free • Non-GMO • Practitioner-formulated
- Bottle Size: 180 Delayed-Release Capsules
Ingredients
- Apple Polyphenols
- Diamine Oxidase (DAO enzyme)
- Lyophilized Ovine Thymus Tissue
- Rutin
- Vitamin B6 (as Pyridoxal 5′-Phosphate)
For amount per serving, please reference the Supplement Facts panel in the product image gallery.
Suggested Use
Take as directed by your healthcare practitioner. For detailed serving information, refer to the Supplement Facts panel in the product image gallery.
Complimentary Pairings
For additional histamine and mast-cell support, combine with Histamine Scavenger and MC Balancer.‡
Gene Variant Support
| Gene | Symbol | Relevant SNPs |
|---|---|---|
| DAO | AOC1 | rs10156191 • rs1049742 • rs1049793 |
References
- Raje N et al. J Asthma. 2014;52(4):353-362. [DOI: 10.3109/02770903.2014.973501]
- Verrall L et al. Mol Psychiatry. 2010;15(2):122-137. [DOI: 10.1038/mp.2009.99]
- Ayuso P et al. Pharmacogenet Genomics. 2007;17(9):687-693. [PMID: 17700358]
- García-Martín E et al. Pharmacogenomics. 2009;10(5):867-883. [DOI: 10.2217/pgs.09.26]
- Music E et al. Clin Transl Allergy. 2011;1(S1):P115. [DOI: 10.1186/2045-7022-1-S1-P115]
- Agundez G et al. PLoS One. 2012;7(11):e47571. [DOI: 10.1371/journal.pone.0047571]
- Maintz L et al. Am J Clin Nutr. 2007;85(5):1185-1196.
- Garcia-Martin E et al. World J Gastroenterol. 2006;12(4):615-620.
- Martner-Hewes PM et al. Am J Clin Nutr. 1986;44(6):907-913.
- Jarisch R et al. Int Arch Allergy Immunol. 1996;110(1):7-12.
Frequently Asked Questions
What does ABP1 Assist (HISTA/GUT) support?
ABP1 Assist (HISTA/GUT) provides nutritional support for the body’s natural metabolism of histamine within the digestive tract. It contains the DAO enzyme, vitamin B6 (as P-5-P), and supporting nutrients that help maintain balanced histamine levels and gastrointestinal comfort.*
Who may benefit from ABP1 Assist?
Individuals who experience sensitivity to histamine-rich foods or environmental triggers, or those seeking support for digestive and immune balance, may benefit from this formula.*
What ingredients are included in ABP1 Assist?
ABP1 Assist combines Diamine Oxidase (DAO) enzyme with vitamin B6 (as Pyridoxal 5′-Phosphate), apple polyphenols, rutin, and lyophilized thymus tissue for comprehensive histamine metabolism support.*
Can ABP1 Assist be taken with other supplements?
Yes. ABP1 Assist pairs well with complementary formulas such as Histamine Scavenger and MC Balancer for additional histamine and mast-cell support.*
Who manufactures ABP1 Assist?
ABP1 Assist (HISTA/GUT) is manufactured by MethylGenetic Nutrition®, a division of Professional Health Products®. It is formulated for healthcare professionals and made under strict quality standards.*
‡This content is for educational and informational purposes only and is not intended as medical advice. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
