What It Is
BH4 Assist is a single-capsule formula combining folate in two reduced forms with a 525 mg blend of royal jelly and SAMe, plus lithium as orotate. Each capsule is a full serving, with 60 in a bottle.
Key Benefits
- Supplies folate at 517 mcg DFE, split between calcium folinate and L-5-methyltetrahydrofolate
- Provides SAMe, supplied from adenosyl methionine tosylate disulfate
- Includes royal jelly, a substance produced by honeybees
- Supplies lithium as lithium orotate at 100 mcg
- Folate has a role in normal amino acid metabolism and normal cell division
- One capsule per serving, with no fillers or flow agents listed
How It Works
Folate is supplied in two forms rather than one: 66% as calcium folinate and 34% as L-5-methyltetrahydrofolate. Both are reduced folates, distinct from folic acid, and the label states the split.
SAMe is supplied from adenosyl methionine tosylate disulfate, a salt form. SAMe is chemically unstable in free form, so supplemental SAMe is always provided as a salt rather than the bare compound.
Royal jelly is a substance produced by honeybees and fed to larvae. It is a whole material rather than an isolated compound.
Featured Ingredients
- Folate, 517 mcg DFE (304 mcg) — 66% calcium folinate, 34% L-5-methyltetrahydrofolate
- Royal jelly — a bee-produced material
- SAMe (S-adenosyl methionine), from adenosyl methionine tosylate disulfate
- Lithium as lithium orotate, 100 mcg
Supplement Facts
Serving Size: 1 Capsule
Servings Per Container: 60
| Amount Per Serving | % Daily Value |
|---|---|
| Folate | 517 mcg DFE (304 mcg), 129% |
| (66% Calcium Folinate & 34% L-5-Methyltetrahydrofolate) | |
| Proprietary Blend | 525 mg, ** |
| Royal Jelly | |
| SAM-e (S-Adenosyl methionine) (from Adenosyl methionine Tosylate Disulfate) | |
| Lithium (Orotate) | 100 mcg, ** |
* Percent Daily Values are based on a 2000 calorie diet.
** Daily Value not established
Other Ingredients: Hypromellose and Water (vegetarian capsule).
Sourcing & Quality
Folate is supplied as two reduced forms with the ratio stated on the label, and SAMe is identified by the specific salt it comes from. The capsule shell is hypromellose, a plant-derived vegetarian capsule, and it is the only other ingredient — no fillers, binders, or flow agents. The formula is gluten-free.
This formula contains royal jelly, a bee product. It is not vegan.
Warnings
- Contains royal jelly. Royal jelly is a bee product and a known allergen. Do not use if you are allergic to bees, bee products, or pollen, or if you have asthma. Severe allergic reactions to royal jelly have been reported.
- Not suitable for vegans.
- Keep out of reach of children.
- Consult your healthcare professional before use if pregnant, nursing, taking medications, or under medical supervision.
- Store in a cool, dry place.
Frequently Asked Questions
Does BH4 Assist contain bee products?
Yes. The formula contains royal jelly, which is produced by honeybees. Royal jelly is a known allergen and severe allergic reactions have been reported, so this product is not suitable for anyone allergic to bees, bee products, or pollen, or for anyone with asthma. It is also not vegan. See the warnings section above.
What is in BH4 Assist?
Each capsule supplies 517 mcg DFE of folate split between calcium folinate and L-5-methyltetrahydrofolate, a 525 mg proprietary blend containing royal jelly and SAMe, and 100 mcg of lithium as orotate. The full panel is listed in the Supplement Facts above.
What form does it come in, and how many servings are in a bottle?
BH4 Assist is supplied in vegetarian capsules with a hypromellose shell. A bottle contains 60 capsules and the serving size is 1 capsule, so a bottle is 60 servings.
Why is the folate listed in two forms?
The label states the folate is 66% calcium folinate and 34% L-5-methyltetrahydrofolate. Both are reduced folates, distinct from folic acid, the synthetic form used in fortified foods. Supplying two forms rather than one is a formulation choice, and stating the ratio on the panel is more detail than most labels give.
What form of SAMe does this contain?
The label specifies SAMe from adenosyl methionine tosylate disulfate. SAMe is chemically unstable in free form and degrades on exposure to moisture and heat, so supplemental SAMe is always supplied as a salt. The tosylate disulfate is one of the salt forms used.
What is royal jelly?
Royal jelly is a substance secreted by honeybees and fed to larvae in the hive. In supplements it is used as a whole material rather than as an isolated compound. Because it comes from bees, it is an allergen for anyone sensitive to bee products or pollen, and it is not vegan.
What are the other ingredients?
Hypromellose and water, which make up the vegetarian capsule shell. No fillers, binders, or flow agents are listed.









