What It Is
Pro SAMe is a single-ingredient formula supplying 200 mg of stabilized S-adenosyl-L-methionine per capsule. The label states it is produced by a special patented process and is gastric acid resistant, with hypromellose and water as the only other ingredients.
Key Benefits
- Supplies 200 mg of S-adenosyl-L-methionine per capsule as a stabilized ion
- SAMe is a compound the body forms from methionine and is used as a methyl donor in normal methylation pathways
- Gastric acid resistant, as stated on the label
- A single ingredient with no fillers, flow agents, or other excipients listed
- One capsule per serving, with 30 servings per bottle
How It Works
S-adenosyl-L-methionine is formed in the body from the amino acid methionine and adenosine triphosphate. It functions as a methyl donor, contributing methyl groups within the body’s normal methylation processes.
SAMe is well known in supplement manufacturing for being unstable — it is sensitive to moisture and heat, and degrades readily unless stabilized. That is why supplemental SAMe is supplied as a salt or stabilized ion rather than in free form. This label specifies a stabilized ion made by a patented process.
The label also states the product is gastric acid resistant, meaning it is formulated to withstand stomach acid rather than dissolving on contact with it.
Featured Ingredients
- SAMe ion (stabilized), 200 mg per capsule — the formula’s only active ingredient
Supplement Facts
Serving Size: 1 Capsule
Servings Per Container: 30
| Amount Per Serving | % Daily Value |
|---|---|
| SAMe Ion (Stabilized) | 200 mg, * |
* Daily Value not established.
Other Ingredients: Hypromellose and water (vegetarian capsule).
Sourcing & Quality
The label states that Pro SAMe is made by a special patented process and is gastric acid resistant. It is a single-ingredient product: aside from the SAMe itself, the only other ingredients are hypromellose and water, which make up the vegetarian capsule shell. There are no fillers, binders, or flow agents. The formula is gluten-free and plant-based.
Warnings
- Keep out of reach of children.
- Consult your healthcare professional before use if pregnant, nursing, taking medications, or under medical supervision.
- Store in a cool, dry place.
Frequently Asked Questions
What is in Pro SAMe?
One ingredient: 200 mg of stabilized SAMe ion per capsule. The only other ingredients are hypromellose and water, which form the vegetarian capsule shell. There are no fillers, binders, or flow agents. The full panel is listed in the Supplement Facts above.
What form does it come in, and how many servings are in a bottle?
Pro SAMe is supplied in vegetarian capsules with a hypromellose shell. A bottle contains 30 capsules and the serving size is 1 capsule, so a bottle is 30 servings.
What is SAMe?
SAMe is short for S-adenosyl-L-methionine, a compound the body forms from the amino acid methionine and adenosine triphosphate. It acts as a methyl donor, meaning it contributes methyl groups within the body’s normal methylation processes.
Why does the label say “stabilized”?
SAMe is chemically unstable in free form and degrades on exposure to moisture and heat. Supplemental SAMe is therefore supplied as a salt or as a stabilized ion rather than as the free compound. This label specifies a stabilized SAMe ion produced by a patented process.
What does “gastric acid resistant” mean?
It means the product is formulated to resist stomach acid rather than dissolving immediately on contact with it. The label states this directly. It is a different approach from a delayed-release capsule, though both address the same general issue of what happens to a supplement in the stomach.
How should it be stored?
Cool and dry, as stated in the warnings. Because SAMe is sensitive to moisture, keeping the bottle sealed and away from humidity matters more for this product than for many others. Avoid storing it in a bathroom or anywhere subject to steam or temperature swings.
