Nitric Oxide Accelerator contains L- arginine & L-citrulline, critical factors needed to support nitric oxide production, along with herbs that support the NOS enzyme production and thereby the production of nitric oxide. Nitric oxide is important in cardiovascular and neurological function, especially so in men’s health. This product is appropriate if there is adequate BH4 and NADPH. If these are deplete, the L-arginine will turn into super-oxide and then the damaging peroxynitrite. If NOS uncoupling is suspected a better first choice would be NOS Assist.